abstract：:With increasing shortage of donor organs and changes in organ allocation systems, there is a considerable need for alternative or supportive techniques in the field of liver transplantation. Liver cell transplantation (LCT) is such an innovative technique that is especially promising for use in children, because it is...

journal_title：Clinical transplantation

authors： Meyburg J,Schmidt J,Hoffmann GF

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Post-transplant gastrointestinal (GI) side effects can impair a patient's quality of life (QoL). This study investigates the improvement in GI side effects and related QoL changes in recipients of liver transplantation (OLT) after converting patients from mycophenolate mofetil (MMF) to enteric-coated mycophe...

journal_title：Clinical transplantation

authors： Doria C,Ramirez CB,Frank AM,Vaccino S,Fraser N,Marino IR

更新日期：2009-11-01 00:00:00

abstract：:Chronic allograft nephropathy (CAN) leads to the majority of late graft loss following renal transplantation. Detection of CAN is often too late to permit early intervention and successful management. Most current strategies for managing CAN rely on minimizing or eliminating calcineurin inhibitors (CNIs) once CAN has ...

journal_title：Clinical transplantation

authors： Campistol JM,Boletis IN,Dantal J,de Fijter JW,Hertig A,Neumayer HH,Oyen O,Pascual J,Pohanka E,Ruiz JC,Scolari MP,Stefoni S,Serón D,Sparacino V,Arns W,Chapman JR

更新日期：2009-11-01 00:00:00

abstract：:Temporary graft dysfunction with gas exchange abnormalities is a common finding during the postoperative course of a lung transplant and is often determined by the post-reimplantation syndrome. Supportive measures including oxygen by mask, inotropes, diuretics, and pulmonary vasodilators are usually effective in non-s...

journal_title：Clinical transplantation

authors： Feltracco P,Serra E,Barbieri S,Persona P,Rea F,Loy M,Ori C

更新日期：2009-09-01 00:00:00

abstract：:In this single-institution study, we compared outcomes in diabetic recipients of living donor (LD) kidney transplants that did vs. did not undergo a subsequent pancreas transplant. Of 307 diabetic recipients who underwent LD kidney transplants from January 1, 1995, through December 31, 2003, a total of 175 underwent a...

journal_title：Clinical transplantation

authors： Kleinclauss F,Fauda M,Sutherland DE,Kleinclauss C,Gruessner RW,Matas AJ,Kasiske BL,Humar A,Kandaswamy R,Kaul S,Gruessner AC

更新日期：2009-08-01 00:00:00

abstract：:From January 2007, we started to perform the tonsillectomy for every patient with recurrent IgA nephropathy (IgAN) after kidney transplantation. Up to September 2008, four recipients with primary IgAN had biopsy-proven recurrent IgAN. They had also progressive hematuria or proteinuria from on the average 14.3 months a...

journal_title：Clinical transplantation

authors： Ushigome H,Suzuki T,Fujiki M,Nobori S,Sakamoto S,Okamoto M,Urasaki K,Yoshimura N

更新日期：2009-08-01 00:00:00

abstract：INTRODUCTION:When a patient who had renal replacement therapy becomes older, an elder donor candidate may be considered as a potential donor for living-related transplantation. Elder donor candidate might have pre-existing disease including mild renal dysfunction, such as proteinuria. Marginally appropriate donors migh...

journal_title：Clinical transplantation

authors： Akioka K,Okamoto M,Ushigome H,Nobori S,Suzuki T,Sakai K,Sakamoto S,Urasaki K,Yanagisawa A,Fukatsu A,Yoshimura N

更新日期：2009-08-01 00:00:00

abstract：:The shortage of kidney donors has led to broadening of the acceptance criteria for deceased donor organs beyond the traditional use of young donors. We determined long-term post-transplant outcomes in recipients of dual expanded criteria donor kidneys (dECD, n = 44) and compared them to recipients of standard criteria...

journal_title：Clinical transplantation

authors： Salifu MO,Norin AJ,O'Mahony C,Sumrani N,Apel A,Ikram M,Alam A,Hayat A,Jindal RM,Friedman EA,Distant DA

更新日期：2009-06-01 00:00:00

abstract：:Using lacerated livers for liver transplantation (LTx) can add an option to the extended donor criteria. We present an LTx case using a severely lacerated liver and review of the literature for reported cases. We used a high-grade lacerated liver from a 19-yr-old brain-dead patient caused by traffic accident. The live...

journal_title：Clinical transplantation

authors： Mehrabi A,Fonouni H,Ahmadi R,Schmied BM,Müller SA,Welsch T,Hallscheidt P,Zeier M,Weitz J,Schmidt J

更新日期：2009-06-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection complicates the post-operative course of patients receiving solid organ transplants. While ganciclovir has significantly reduced the direct effects of CMV infection, some patients cannot tolerate the optimal therapeutic exposure required for CMV prevention and treatment. Few reports dir...

journal_title：Clinical transplantation

authors： Danziger-Isakov L,Mark Baillie G

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Our objective is to evaluate whether hyperglycemia in the first 48 h after renal transplantation is independently associated with rejection, post-operative infection and post-transplant diabetes mellitus (PTDM) in a retrospective cohort study. METHODS:Patients who received a renal transplant in our hospital...

journal_title：Clinical transplantation

authors： van den Berg TJ,Bogers H,Vriesendorp TM,Surachno JS,DeVries JH,ten Berge IJ,Hoekstra JB

更新日期：2009-03-01 00:00:00

abstract：INTRODUCTION:Aortoiliac pathology in kidney allograft recipients is not rare but treatment timing is controversial. As most publications on this topic are case reports its difficult to evaluate long-term outcomes of those clinical challenges. Herein we report long-term results of these procedures. METHODS:From 1970 to...

journal_title：Clinical transplantation

authors： Tsivian M,Neri F,Nardo B,Bertelli R,Cavallari G,Fuga G,Faenza A

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:In adult living-donor liver transplantation (LDLT), the assessment of the graft functional reserve is very important. We evaluated the graft functional reserve by technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl-human serum albumin ((99m)Tc-GSA) liver scintigraphy. PATIENTS AND METHOD:From May ...

journal_title：Clinical transplantation

authors： Iida T,Isaji S,Yagi S,Hori T,Taniguchi K,Ohsawa I,Mizuno S,Usui M,Sakurai H,Yamagiwa K,Yamakado K,Uemoto S

更新日期：2009-03-01 00:00:00

abstract：:Subclinical rejection (SCR) is quite common early following renal transplantation and decreases progressively with time. The immunological profile of the recipient, the immunosuppressive regimen used, and the occurrence of prior episodes of clinical acute rejection (AR) are all risk factors for SCR. SCR, in turn, is a...

journal_title：Clinical transplantation

authors： El-Amm JM,Gruber SA

更新日期：2009-03-01 00:00:00

abstract：:Steroid-resistant acute rejection (SR-AR) and ductopenic rejection (DR) after liver transplantation are infrequent, but difficult to manage. We performed a retrospective review of patients with SR-AR or DR treated with sirolimus-based therapy. Since 2002, we have treated five patients with SR-AR and eight patients wit...

journal_title：Clinical transplantation

authors： Lladó L,Fabregat J,Castellote J,Ramos E,Torras J,Serrano T,Figueras J,Rafecas A

更新日期：2009-01-01 00:00:00

abstract：:The combination of methotrexate and cyclosporine A (MTX-CSA) is the standard regimen for the prevention of graft vs. host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (allo-SCT) from HLA-identical siblings. Mycophenolate mofetil and CSA (MMF-CSA) combination has been successfully used for GV...

journal_title：Clinical transplantation

authors： Ostronoff F,Ostronoff M,Souto-Maior AP,Domingues M,Sucupira A,Manso DA,de Lima AK,Monteiro PG,Florêncio R,Calixto R

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:To analyze the characteristics of tuberculosis (TB) in Southern Chinese renal transplant recipients, and summarize the corresponding experiences in diagnosis and management. METHOD:Retrospectively study 41 documented post-transplant TB cases out of the 2333 patients who received kidney transplantation in th...

journal_title：Clinical transplantation

authors： Chen SY,Wang CX,Chen LZ,Fei JG,Deng SX,Qiu J,Li J,Chen GO,Fu HM,Xie CM

更新日期：2008-11-01 00:00:00

abstract：:Mycophenolic acid (MPA) dose reduction is associated with increased risk of rejection and graft loss in renal transplantation. This analysis investigated the impact of MPA dose changes with enteric-coated mycophenolate sodium (EC-MPS) or mycophenolate mofetil (MMF) in de novo heart transplant recipients. In a 12-month...

journal_title：Clinical transplantation

authors： Segovia J,Gerosa G,Almenar L,Livi U,Viganò M,Arizón JM,Yonan N,Di Salvo TG,Renlund DG,Kobashigawa JA,ERL 2401 Study Group.

更新日期：2008-11-01 00:00:00

abstract：:In renal transplant patients receiving mycophenolate mofetil (MMF), maintaining an adequate dosing regimen has been shown to maximize short- and long-term outcomes. Gastrointestinal (GI) adverse events associated with MMF are frequent, and lead to MMF dose reduction or withdrawal in 40-50% of cases. Among MMF-treated ...

journal_title：Clinical transplantation

authors： Bunnapradist S,Ambühl PM

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas are increasingly recognized in clinical practice. There are no published data suggesting a management approach for the potential organ transplant recipient with the incidental finding of this pre-malignant lesion. METHODS:The recipient was a 6...

journal_title：Clinical transplantation

authors： Fridell JA,Vianna R,Mangus RS,Kazimi M,Hollinger E,Joseph Tector A

更新日期：2008-09-01 00:00:00

abstract：UNLABELLED:Enteric-coated mycophenolate sodium (MPS) has been developed to help circumvent the upper gastrointestinal side-effects of mycophenolic acid by facilitating drug release in the small intestine. Many questions regarding the side-effect profile of MPS remain. Therefore, the purpose of this study is to review a...

journal_title：Clinical transplantation

authors： Hardinger KL,Hebbar S,Bloomer T,Murillo D

更新日期：2008-09-01 00:00:00

abstract：:Acute rejection (AR) superimposed upon delayed graft function (DGF) following renal transplantation worsens graft outcomes. However, risk factors for AR in patients displaying DGF remain unclear. In this study, 71 patients displaying DGF >/= 5 d were investigated. All received cyclosporine, adjunctive azathioprine or ...

journal_title：Clinical transplantation

authors： Moore J,Tan K,Cockwell P,Krishnan H,McPake D,Ready A,Mellor S,Hamsho A,Ball S,Lipkin G,Borrows R

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Chronic renal failure (CRF) is a common complication of calcineurin inhibitor (CNI)-based immunosuppression following cardiac transplantation (HTx). The aim of this prospective study was to evaluate the impact of an immunosuppressive conversion from CNIs to mycophenolate mofetil (MMF) and steroids in cardiac...

journal_title：Clinical transplantation

authors： Groetzner J,Kaczmarek I,Schirmer J,Uberfuhr P,Gulbins H,Daebritz S,Meiser B,Reichart B

更新日期：2008-09-01 00:00:00

abstract：:We investigated tolerability and efficacy of ezetimibe treatment (10 mg/d) in 25 heart allograft recipients already on stable statin therapy. Total cholesterol (TC), low-density cholesterol (LDL-C), high-density cholesterol (HDL-C), triglycerides (TG), immunosuppressant drug levels, laboratory and clinical parameters ...

journal_title：Clinical transplantation

authors： Konstandin MH,Blessing E,Doesch A,Ammon K,Koch A,Wabnitz GH,Gleissner CA,Remppis A,Katus HA,Dengler TJ

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND/AIM:The aim of this study was to determine whether the expression of CD25, CD28 and CD38 (which reflects the degree of T-cell activation) by peripheral blood mononuclear cells constitutes a useful means of measuring the immune status of liver transplant recipients. METHODS:Fifty-two patients enrolled in a p...

journal_title：Clinical transplantation

authors： Boleslawski E,BenOthman S,Grabar S,Correia L,Podevin P,Chouzenoux S,Soubrane O,Calmus Y,Conti F

更新日期：2008-07-01 00:00:00

abstract：:The purpose of this review was to evaluate the case reports with lymphoproliferative disorders exclusively localized in the allograft transplanted kidney. We also report a rare case of diffuse large B-cell lymphoma originated from the lymphocytes of the recipient with exclusive localization in the kidney allograft. We...

journal_title：Clinical transplantation

authors： Cobo F,García C,Talavera P,Ruiz-Cabello F,Bravo J,Concha A

更新日期：2008-07-01 00:00:00

abstract：:We performed a systematic search of the literature using the MEDLINE (through 2006) database to identify the patient-reported outcome measures of quality of life (QOL) used most often in the renal transplant literature. After applying limits and reviewing references, we identified 338 renal transplant articles with a ...

journal_title：Clinical transplantation

authors： Butt Z,Yount SE,Caicedo JC,Abecassis MM,Cella D

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Arterial stiffness and left ventricular hypertrophy (LVH) are major independent risk factors for cardiovascular disease in healthy and renal population. In this study, we aimed to investigate comparative long-term effects of renal transplantation (RTx) and of hemodialysis (HD) on both arterial stiffness and ...

journal_title：Clinical transplantation

authors： Keven K,Calayoglu R,Sengul S,Dincer I,Kutlay S,Erturk S,Erbay B,Nergizoglu G

更新日期：2008-05-01 00:00:00

abstract：:Hepatic allograft rejection still remains an important problem following liver transplantation. Early acute rejection, occurring within three months of transplant, is a common event and usually of lesser significance with respect to prognosis than other non-immune-related post-transplant morbidities. However, little i...

journal_title：Clinical transplantation

authors： Uemura T,Ikegami T,Sanchez EQ,Jennings LW,Narasimhan G,McKenna GJ,Randall HB,Chinnakotla S,Levy MF,Goldstein RM,Klintmalm GB

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Recently, we described a significant decrease in donor-specific cytotoxic T-lymphocyte precursor frequency (CTLpf) after discontinuation of calcineurin inhibitors (CNI), while the proliferative capacity in mixed lymphocyte culture (MLC), and the number of interferon-gamma (IFN-gamma) producing cells (pc) in ...

journal_title：Clinical transplantation

authors： van Besouw NM,van de Wetering J,van der Mast BJ,de Kuiper R,Baan CC,Weimar W

更新日期：2008-03-01 00:00:00

abstract：INTRODUCTION:A long-term prospective randomized trial evaluating alemtuzumab, a humanized anti-CD52 monoclonal antibody, in a predominantly non-Caucasian population has yet to be reported. METHODS:Ninety deceased donor (DD) first renal transplant recipients were randomized into three different antibody induction group...

journal_title：Clinical transplantation

authors： Ciancio G,Burke GW,Gaynor JJ,Roth D,Kupin W,Rosen A,Cordovilla T,Tueros L,Herrada E,Miller J

更新日期：2008-03-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is highly prevalent in renal transplant candidates; however, its effect on the transplant outcome is still controversial. The aim of the present study was to determine the effect of HCV infection in the outcome of kidney transplantation in a single transplant center. The study populat...

journal_title：Clinical transplantation

authors： Arango J,Arbelaez M,Henao J,Mejia G,Arroyave I,Carvajal J,Garcia A,Gutierrez J,Velásquez A,Garcia L,Aguirre C

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The goal of immunosuppressive therapy in heart transplantation is to maximize safety and efficacy while minimizing morbidity and mortality. We now have numerous drug combinations, but few have been compared with each other. AIM:To compare various immunosuppressive regimens assessing morbidity and mortality ...

journal_title：Clinical transplantation

authors： Aguero J,Almenar L,Martínez-Dolz L,Moro JA,Rueda J,Raso R,Chamorro C,Sanchez JM,Salvador A

更新日期：2008-01-01 00:00:00

abstract：:Measurement of indocyanine green plasma disappearance rate (PDR(ICG)) has been suggested as a meaningful liver function parameter. However, there are only very limited data concerning its value in the monitoring of graft dysfunction (GDF) and primary non-function (PNF) especially during molecular absorbent recirculati...

journal_title：Clinical transplantation

authors： Scheingraber S,Richter S,Igna D,Girndt M,Flesch S,Kleinschmidt S,Schilling MK

更新日期：2007-11-01 00:00:00

abstract：:Renal transplantation is presently the best treatment for end-stage renal disease, although considered contraindicated for elderly patients. However, more investigation is needed due to higher life expectancy rates of the general population and the increasing number of over 60-yr-old patients with chronic renal failur...

journal_title：Clinical transplantation

authors： Mendonça HM,Dos Reis MA,de Castro de Cintra Sesso R,Câmara NO,Pacheco-Silva A

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Methamphetamine (MA) has cumulative deleterious effects on multiple organ systems. A history of MA exposure in kidney donors may affect adversely graft function in recipients. METHODS:Between September 2000 and March 2004, all deceased kidney donors were identified from the local registry (97 donors). Twent...

journal_title：Clinical transplantation

authors： Inouye DS,Kickertz K,Wong LL

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:BK virus nephropathy (BKVN) has been proposed as an important cause of allograft dysfunction and loss in kidney allograft recipient over the last decade. Intense immunosuppression and tubular injury have been shown to promote the replication of polyomavirus. 15-deoxyspergualin (DSG), an effective immunosuppre...

journal_title：Clinical transplantation

authors： Shi Y,Moriyama T,Namba Y,Yamanaka M,Hanafuse T,Imamura R,Ichimaru N,Oka K,Kyo M,Tian Y,Takahara S,Ichikawa S,Okuyama A

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Abnormal mineral metabolism is not uncommon after renal transplant (TXP). In dialysis patients, elevated serum phosphorous (P), calcium (Ca), CaP product, and parathyroid hormone (PTH) are associated with increased morbidity and mortality. The effect of these abnormalities on recipient and graft survival aft...

journal_title：Clinical transplantation

authors： Egbuna OI,Taylor JG,Bushinsky DA,Zand MS

更新日期：2007-07-01 00:00:00

abstract：INTRODUCTION:The aim of this paper was to review the outcomes of cardiac transplantation with regards to short- and long-term survival, focusing particularly on patients who receive organs with long ischemic times and the resource utilization necessary to support such patients through their postoperative period. METHO...

journal_title：Clinical transplantation

authors： Marasco SF,Esmore DS,Richardson M,Bailey M,Negri J,Rowland M,Kaye D,Bergin PJ

更新日期：2007-05-01 00:00:00

abstract：:The progression of HCV-related disease is particularly aggressive in the post-transplantation setting. Recipients with recurrent HCV infection undergo repeated liver biopsies in order to estimate disease progression. A strong association was found between serum immunoglobulins levels and hepatic fibrosis in non-transp...

journal_title：Clinical transplantation

authors： Schmilovitz-Weiss H,Cohen M,Pappo O,Sulkes J,Braun M,Tur-Kaspa R,Ben-Ari Z

更新日期：2007-05-01 00:00:00